Treatment for malignant mesothelioma is always evolving. Clinical trials are research studies that are used to test how well new medical approaches work for those enlisted in the trial. Therefore, mesothelioma clinical trials are used to determine new effective treatment approaches for those who have been diagnosed with mesothelioma. There is still a lot more research that needs to be done on mesothelioma treatment and clinical trials are a good way to determine the best possible treatments.
Mesothelioma clinical trials are important because they can help people living with cancer to live longer and can help to improve their quality of life.
Testing the Value of Adding Surgery after the Usual Treatment of Patients with Stage I-IIIA Sarcomatoid Mesothelioma
There are currently a multitude of active mesothelioma clinical trials that are available for mesothelioma victims in Pennsylvania. One specific clinical trial is Testing the Value of Adding Surgery after the Usual Treatment (Immunotherapy) for Patients with Stage I-IIIA Sarcomatoid Mesothelioma. This is a phase II trial with the purpose of evaluating the safety and effectiveness of adding surgery after immunotherapy. As with any clinical trial, there are criteria that must be met to enroll in this mesothelioma clinical trial. Some criteria for inclusion include that the person must be diagnosed with sarcomatoid mesothelioma, there must be no prior treatment, the patient must not be pregnant, and they must be above 18 years old.
Those who are excluded from this trial are patients with chest wall invasion, peritoneal spread, involvement of pleural invasion, and there can be no history of interstitial lung disease. This mesothelioma clinical trial is available in Chadds Ford, Pennsylvania at the Christian Care Health System- Concord Health Center.
Sacituzumab Govitecan for the Treatment of Patients with Diffuse Pleural Mesothelioma
Another current mesothelioma clinical trial that is available to mesothelioma patients in Pennsylvania is the Sacituzumab Govitecan for the Treatment of Patients with Diffuse Pleural Mesothelioma clinical trial. This is a phase II trial that tests the efficacy of how sacituzumab govitecan-hziy works in treating patients who have been diagnosed with diffuse pleural mesothelioma. Sacituzumab govitecan is an antibody linked to a chemotherapy drug. This is a form of targeted therapy. In order to enroll in the trial, the patient must be atleast 18 years old, they must have a confirmed diffuse pleural mesothelioma diagnosis, they must have gotten at least one systemic therapy treatment in the past, and they must consent to have a biopsy done, among other criteria. There are locations in New Jersey, right outside of Pennsylvania, in which this clinical trial is available. These locations include Memorial Sloan Kettering Basking Ridge in Basking Ridge, New Jersey, Memorial Sloan Kettering Monmouth, in Middletown, New Jersey, and Memorial Sloan Kettering Bergen, in Montvale, New Jersey.
Pembrolizumab and Intensity-Modulated Pleural Radiation Therapy for the Treatment of Unresectable Malignant Mesothelioma
Another mesothelioma clinical trial that is available near Pennsylvania is the Pembrolizumab and Intensity-Modulated Pleural Radiation Therapy for the Treatment of Unresectable Malignant Mesothelioma clinical trial. This is a phase I trial that aims to find the best dose of intensity modulated pleural radiation therapy and to look at its effect when given with pembrolizumab. This is used to treat patients with malignant pleural mesothelioma whose tumor(s) cannot be removed through surgery. Pembrolizumab is a monoclonal antibody and if it is given with radiation therapy it may kill more cancer cells.
To enroll in this clinical trial, the person must have a confirmed pathological diagnosis of malignant pleural mesothelioma, the tumor(s) must be unresectable, and there must have been at least one line of systemic therapy in the past. Locations near Pennsylvania where this clinical trial is available are Memorial Sloan Kettering Basking Ridge in Basking Ridge, New Jersey, Memorial Sloan Kettering Monmouth in Middletown, New Jersey, and Memorial Sloan Kettering Bergen in Montvale, New Jersey.
These mesothelioma clinical trials could be promising for future research and future effective combinations of treatment.
If you or a loved one has been diagnosed with mesothelioma or another asbestos-related disease, check out our website for more information. To learn more, please call us at (800) 505-6000 or fill out our simple contact form. We help mesothelioma victims in Pennsylvania.
Sources:
https://www.cancer.gov/research/participate/clinical-trials-search/r?loc=1&rl=1&t=C3786&z=19003
