The prognosis for mesothelioma has typically not been very promising, however, new research and clinical studies show that there is hope for better outcomes for patients who have been diagnosed with mesothelioma. Current research can be used to inform future treatment-based decisions.

Mesothelioma is a rare and aggressive form of cancer that develops due to asbestos fibers being lodged in certain areas of the body. This cancer most commonly originates in the lining of the lungs and is associated with shortness of breath, cough, weight loss, and fatigue. Other even more rare forms of mesothelioma begin in the lining of the abdomen, the lining of the heart, and the testicles.

Standard Types of Treatment

Mesothelioma is currently an incurable cancer. That being the case, there are different treatment options that have been traditionally used that can prolong a patient’s life or give them a better quality of life. Typical mesothelioma treatment options include:

New Discoveries

Recently, it has been discovered that genetic signatures can help with deciding on potential treatments along with results from a clinical study showing that novel T-cell therapy can enable tumor regression in particular patients. These discoveries could result in a better prognosis for mesothelioma patients in the future.

A new drug has been introduced in a clinical trial that shows promising results. The drug is called ADI-PEG20 and is used in combination with chemotherapy. A study called the ATOMIC-meso trial was conducted at 43 different places in five countries over the span of four years. What was learned from this study led to the development of ADI-PEG20, which works to deplete arginine levels in the bloodstream, leading to the growth of tumor cells to be suppressed.

Pembrolizumab with pemetrexed platinum chemotherapy was approved by the FDA as a first-line form of treatment for those with malignant pleural mesothelioma whose tumors cannot be removed through surgery.

There are currently other drugs being studied and other forms of treatment being looked into that could help with the overall survival of mesothelioma victims.

Help is on the Way

Overall, it is vital that research continues to be done to help determine the best possible treatment for those who have been diagnosed with mesothelioma. Although a rare form of cancer, there are still approximately 3,000 cases of mesothelioma each year in the US. Continued research and clinical trials will help us get closer to finding the most appropriate forms of treatment for each person.

If you or a loved one has been diagnosed with mesothelioma, or another asbestos-related disease, we are here to help get you compensated for your diagnosis, which can help pay for medical expenses, as treatment can be very costly. To find out more about how we can help you call us at (800) 505-6000 or fill out our contact form. We provide information and legal services to those in Pennsylvania who have been affected by an asbestos-related disease.

Sources:

https://ccr.cancer.gov/news/milestones-2024/two-strikes-against-mesothelioma

https://www.theguardian.com/science/2024/feb/15/drug-offers-wonderful-breakthrough-in-treatment-of-asbestos-linked-cancer

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