BAP1 Gene: Regulating Mesothelioma

Key Takeaways The BAP1 gene is a tumor-suppressing gene that controls critical cellular processes — including tumor growth inhibition, programmed cell death, and DNA repair. It is mutated in approximately 60–70% of all mesothelioma cases. A BAP1 mutation can be inherited (germline mutation) or caused by external factors like asbestos exposure. Either way, the mutation […]